Clinical trial of deglydyrrhizinized liquorice in gastric ulcer.

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Clinical trial of deglycyrrhizinized liquorice in gastric ulcer.

In the past twenty years evidence has accumulated that liquorice and related compounds accelerate the rate of healing of gastric ulcers. Powdered succus liquiritiae (Revers, 1948) and glycyrrhiza extract (Schulze, Franke, and Keller, 1954; Ferenbach, 1954; Ohrt, 1955) were shown to be beneficial in patients with gastric ulcer but adequately controlled clinical trials of liquorice extracts were ...

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Clinical trial of deglycyrrhizinised liquorice in gastric ulcer.

Ninety-six patients with gastric ulcer were randomly allocated to treatment either with deglycyrrhizinised liquorice or placebo. After four weeks no differences were found between the treatment groups in the proportions with complete healing, whether assessed by gastroscopy or radiology, or in the percentage reduction in ulcer area, or in clinical improvement.

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Double-blind trial of deglycyrrhizinated liquorice in gastric ulcer.

In order to investigate further the reported beneficial effect of deglycyrrhizinated liquorice in gastric ulcer, a trial with a double-blind, cross-over design was performed. The patients were treated during two consecutive periods of four weeks each with either liquorice extract during the first period and placebo during the second or placebo during the first period and liquorice during the se...

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Evaluation of Anti-ulcer Activity of Echinops Persicus on Experimental Gastric Ulcer Models in Rats

Extract of Echinops persicus is traditionally used for a long time in Iran for treatment of cough and constipation. This extract is produced by activity of bug (Situphilus spp.) on the plant. We documented its anti-tussive effect in rats in our previous study. The aim of this study was to assess the anti-ulcer effect of Echinops persicus in an animal model. In this study we evaluated anti-ulcer...

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ژورنال

عنوان ژورنال: Gut

سال: 1969

ISSN: 0017-5749

DOI: 10.1136/gut.10.4.299